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Bottinelli Roberto

Professore Ordinario
Fisiologia Umana
Via Forlanini 6
27100 Pavia

Sito internethttp://www-3.unipv.it/fisumana/bottinelli
Orari di ricevimentoDa concordare per e-mail
Cell Physiology, Muscle Physiology, Cardiovascular Physiology, Endocrine Physiology, Respiratory Physiology, Neurophysiology, Kidney Physiology, Gastroenterologic Physiology - Corso di Laurea in Medicina - Harvey

Neurofisiologia - Corso di Laurea in Medicina e Chirurgia – Golgi
SeminariUpdates in Cellular Physiology – ADE Harvey Course
CurriculumCV Roberto Bottinelli
PubblicazioniCapitanio M, Canepari M, Cacciafesta P, Lombardi V, Cicchi R, Maffei M, Pavone FS & Bottinelli R. (2006). Two independent mechanical events in the interaction cycle of skeletal muscle myosin with actin. Proc Natl Acad Sci U S A 103, 87-92.

Sampaolesi M, Torrente Y, Innocenzi A, Tonlorenzi R, D'Antona G, Pellegrino MA, Barresi R, Bresolin N, De Angelis MG, Campbell KP, Bottinelli R & Cossu G. (2003). Cell therapy of alpha-sarcoglycan null dystrophic mice through intra-arterial delivery of mesoangioblasts. Science 301, 487-492.

Bottinelli R & Reggiani C. (2000). Human skeletal muscle fibres: molecular and functional diversity. Prog Biophys Mol Biol 73, 195-262.

Bottinelli R, Coviello DA, Redwood CS, Pellegrino MA, Maron BJ, Spirito P, Watkins H & Reggiani C. (1998). A mutant tropomyosin that causes hypertrophic cardiomyopathy is expressed in vivo and associated with an increased calcium sensitivity. Circ Res 82, 106-115.

Bottinelli R, Schiaffino S & Reggiani C. (1991). Force-velocity relations and myosin heavy chain isoform compositions of skinned fibres from rat skeletal muscle. J Physiol 437, 655-672.

Collaborazioni• M. Geeves, University of Kent, UK: kinetics of acto-myosin interactions in skeletal myosin isoforms
• F. Pavone and M. Capitanio, LENS, Florence: single molecule mechanics of skeletal myosin isoforms
• C. Reggiani, University of Padova, Italy: intracellular signaling during skeletal muscle adaptations
• G. Cossu, University College, London, UK; cell therapy for Muscular Dystrophies
• Diana Conte Camerino, University of Bari, Italy; disuse muscle atrophy
• Marco Narici, University of Nottingham, UK; skeletal muscle and ageing